Vitamina D protege contra o coronavírus? Especialista explica!

Campanha de órgão britânico incentiva suplementação de vitamina D

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Segundo especialistas, ela evitaria a incidência de doenças como diabetes , tuberculose, esclerose múltipla e raquitismo.

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Royal College of Paediatrics and Child Health, RCPCH, órgão que supervisiona a saúde infantil no Reino Unido, está lançando uma campanha que incentiva a população a consumir diariamente doses de vitamina D para fortalecer a saúde.

Segundo os estudiosos, alguns dos benefícios seriam o aumento da incidência de diabetes, tuberculose, esclerose múltipla e raquitismo, doença que provoca e enfraquecimento e deformação dos ossos.

Normalmente obtido pela luz solar e por alimentos como peixes oleosos, ovos e cogumelos, o nutriente evita dores ósseas e musculares, além dos inchaços nos punhos e costelas.

Em países como Estados Unidos, Canadá e Finlândia a ingestão de vitamina D já é mais comum.

Segundo especialistas do RCPCH, consumir mais peixe ou aumentar a incidência de radiações solares não vão solucionar, já que elas oferecem apenas 10% das necessidades.

Sendo assim, a suplementação vitamínica seria a melhor solução.

Fonte: http://www.sesifarmacias.com.br/servicos/dicas/detalhes/campanha-de-orgao-britanico-incentiva-suplementacao-de-vitamina-d

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Vitamina D status no diagnóstico de câncer do seio. Vitamin D status at breast cancer diagnosis: Correlation with tumor characteristics?

Breast cancer awareness

Breast cancer awareness (Photo credit: AslanMedia)

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Sobre Vitamina D, assista ao vídeo do Programa Sem Censura:

Vitamina D – Sem Censura – Dr. Cicero Galli Coimbra e Daniel Cunha

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“In conclusion, this study suggests that vitamin D supplementation and sun exposure prior to breast cancer diagnosis helps with survival and reducing the size of breast tumors. Here, levels above 30 ng/mL were better than lower levels.”

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July 17, 2012 — Brindusa Vanta, MD

A new study confirms that healthy blood levels of vitamin D are important in women diagnosed with breast cancer and it also reveals new findings regarding the benefits of vitamin D for this condition.

Hatse S et al. Vitamin D status at breast cancer diagnosis: correlation with tumor characteristics, disease outcome and genetic determinants of vitamin D insufficiency. Carcinogenesis, 2012.

In this study, featured in the May 2012 issue of Carcinogenesis, a group of scientists out of Catholic University Leuven in Belgium evaluated the relation between vitamin D status and breast cancer. They wanted to know if vitamin D status at the time of diagnosis correlates or influences tumor characteristics, survival, and cancer relapse. Furthermore, they wanted to know if any of this was influenced by vitamin D related genes.

The researchers performed blood tests on 1800 early stage breast cancer patients at the time they received the diagnosis (before starting any treatment). They evaluated the blood levels of vitamin D (25OHD levels) and looked at the specific genes related to vitamin D pathway.

25OHD levels of >30 ng/mL were classified as “high” and were observed in 35.9% of the participants. 31.7% of women had “intermediate” 25OHD levels- between 20-30 ng/mL and 32.4% of the women had “low” 25OHD levels, classified as <20 ng/mL.

They made the following observations:

1. Low levels of 25OHD serum were significantly associated with larger tumors (at the time of the diagnosis) and high levels of 25OHD levels were associated with smaller breast tumors. This is the most remarkable finding, because previous studies did not show the link between vitamin D levels and tumor size.

2. High blood levels of vitamin D at the time of diagnosis were significantly associated with a better overall survival and disease-specific survival. Basically this means that women with low serum 25OHD levels at breast cancer diagnosis have an increased risk of death from any (breast cancer related or unrelated) cause. There was noted some improvement in the disease-free interval as well.

3. It is already known that the incidence of breast cancer is higher in postmenopausal women (60 % of women diagnosed with breast cancer are menopausal). Vitamin D deficiency is also more common after menopause.

This study found that high levels of vitamin D significantly improved the disease outcome among postmenopausal women (compared with those women who had low levels of 25OHD).

4. Researchers also found that that vitamin D related genes significantly influence the serum levels of 25OHD, but did not correlate with tumor size or survival.

This fits with past research nicely. Past studies have found:
An increased risk of developing breast cancer with higher latitude, low sun exposure and low vitamin D status.
A meta-analysis indicated a slight decrease in breast cancer risk following preventive vitamin D intake.
A large randomized, placebo-controlled study from Women’s Health Initiative (WHI) showed that supplementation with vitamin D and calcium reduced the risk of breast and colorectal cancers.

In conclusion, this study suggests that vitamin D supplementation and sun exposure prior to breast cancer diagnosis helps with survival and reducing the size of breast tumors. Here, levels above 30 ng/mL were better than lower levels.

Fonte: http://blog.vitamindcouncil.org/2012/07/17/vitamin-d-status-at-breast-cancer-diagnosis-correlation-with-tumor-characteristics/

 

Asma e Vitamina D – Vitamin D deficiency and poorer lung function in asthmatic children treated with steroids

Asthma in America

Asthma in America (Photo credit: GDS Infographics)

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Assista à entrevista sobre este assunto, em português:

Vitamina D – Sem Censura – Dr. Cicero Galli Coimbra e Daniel Cunha

Ao vídeo:

Vitamina D – Por uma outra terapia (Vitamin D – For an alternative therapy)

Leia:

Vitamina D pode revolucionar o tratamento da esclerose múltipla

 

 

Vitamin D deficiency is associated with poorer lung function in asthmatic children treated with inhaled corticosteroids, according to a new study from researchers in Boston.

“In our study of 1,024 children with mild to moderate persistent asthma, those who were deficient in vitamin D levels showed less improvement in pre-bronchodilator forced expiratory volume in 1 second (FEV1) after one year of treatment with inhaled corticosteroids than children with sufficient levels of vitamin D,” said Ann Chen Wu, MD, MPH, assistant professor in the Department of Population Medicine at Harvard Medical School and Harvard Pilgrim Health Care Institute. “These results indicate that vitamin D supplementation may enhance the anti-inflammatory properties of corticosteroids in patients with asthma.”

The findings were published online ahead of print publication in the American Thoracic Society‘s American Journal of Respiratory and Critical Care Medicine.

The study was conducted using data from the Childhood Asthma Management Program, a multi-center trial of asthmatic children between the ages of five and 12 years who were randomly assigned to treatment with budesonide (inhaled corticosteroid), nedocromil, or placebo. Vitamin D levels were categorized as deficient (≤ 20 ng/ml), insufficient (20-30 ng/ml), or sufficient (> 30 ng/ml).

Among children treated with inhaled corticosteroids, pre-bronchodilator FEV1 increased during 12 months of treatment by 330 ml in the vitamin D insufficiency group and 290 ml in the vitamin D sufficiency group, but only 140 ml in the vitamin D deficient group.

Compared with children who were vitamin D sufficient or insufficient, children who were vitamin D deficient were more likely to be older, be African American, and have higher BMI. Compared with being vitamin D deficient, being vitamin D sufficient or insufficient was associated with a greater change in pre-bronchodilator FEV1 over 12 months of treatment after adjustment for age, gender, race, BMI, history of emergency department visits, and season that the vitamin D specimen was drawn.

The study had some limitations, including a small sample size of 101 vitamin D deficient children, and the investigators only studied vitamin D levels at one time point.

“Our study is the first to suggest that vitamin D sufficiency in asthmatic children treated with inhaled corticosteroids is associated with improved lung function,” said Dr. Wu. “Accordingly, vitamin D levels should be monitored in patients with persistent asthma being treated with inhaled corticosteroids. If vitamin D levels are low, supplementation with vitamin D should be considered.”
Source: American Thoracic Society

http://www.sciencecodex.com/vitamin_d_deficiency_and_poorer_lung_function_in_asthmatic_children_treated_with_steroids-94927

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